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Simparica Trio Dog Large 44.3 - 88lbs Green

As low as $70.39

Simparica Trio Dog Large 43 - 88lbs Green 

Embark on a journey of unparalleled protection and well-being for your large canine companion with Simparica Trio Dog Large 43 - 88lbs Green the gold standard in all-in-one parasite protection. Specially tailored for dogs weighing between 43 and 88lbs, this revolutionary chewable redefines comprehensive care, addressing fleas, ticks, heartworms, and intestinal parasites with a powerful triple-action formula. Simparica Trio has firmly secured its position as the world's number 1 selling all-in-one protection for large dogs, and here's why.


Key Benefits:

  • Triple Defense Formula: Simparica Trio's cutting-edge formulation combines three potent active ingredients Sarolaner, Moxidectin, and Pyrantel. This triple defense system ensures a formidable shield against a wide spectrum of parasites, providing your large dog with unparalleled protection.
  • Extended Flea and Tick Protection: Bid farewell to the constant battle against fleas and ticks. Simparica Trio offers an extended 35-day protection window, effectively eliminating these pesky parasites and preventing reinfestations, allowing your furry friend to enjoy life to the fullest.
  • Heartworm Prevention: Simparica Trio stands as a guardian against heartworm disease, a potentially fatal condition. Moxidectin, a key component, disrupts the heartworm life cycle, preventing the development of this insidious threat and safeguarding your dog's cardiovascular health.
  • Intestinal Parasite Control: Beyond external parasites, Simparica Trio takes a comprehensive approach by addressing internal threats. Pyrantel, another integral ingredient, tackles and controls roundworms and hookworms, promoting optimal gastrointestinal health for your large dog.
  • Palatable and Convenient: Administration becomes a breeze with Simparica Trio's palatable chewable format. Infused with a tempting beef flavor, the chewable transforms medication time into a treat session, ensuring compliance and making the monthly routine enjoyable for both pet and owner.
  • Waterproof Assurance: Simparica Trio's waterproof formulation ensures that its efficacy remains intact, even in the face of water-related activities. Whether your dog loves to splash in puddles or enjoys a swim, rest assured that Simparica Trio continues to provide robust protection.

Simparica Trio: The Best All-in-One Protection for Large Dogs

Simparica Trio has earned the trust of many pet owners as the premier choice for all-in-one protection for large dogs due to its exceptional efficacy and numerous advantages. This groundbreaking solution simplifies the complexities of parasite control with a single chewable, endorsed by veterinary professionals worldwide. Its triple-action formula not only streamlines the monthly protection routine but also addresses a spectrum of health concerns, ensuring that your large dog receives holistic care beyond mere parasite prevention.

Pet owners across the globe rely on Simparica Trio for its proven track record, unwavering commitment to excellence, and dedication to the well-being of furry family members. Join the ranks of satisfied pet parents who choose Simparica Trio. Elevate your dog's protection game and provide the care they deserve with Simparica Trio where innovation meets peace of mind.



While Simparica Trio proves highly effective and enjoys widespread trust as a parasite control solution for large dogs, it is essential to adhere to the recommended dosage and administration guidelines as provided by your veterinarian. Be sure to select the appropriate variant based on your dog's weight range and administer the chewable according to the instructions on the packaging or the guidance of your veterinarian. If your dog is taking other medications, consult with your veterinarian to address any concerns about potential interactions before initiating Simparica Trio. Additionally, diligently observe your dog for any signs of adverse reactions, and promptly seek veterinary attention if any unusual symptoms manifest.

Safeguard your large dog with the ultimate all-in-one parasite protection Simparica Trio. More than just a chewable, it stands as a comprehensive care solution, ensuring your dog remains healthy, happy, and well-protected.

Animal Type
Breed Size
  • Sarolaner
  • Moxidectin
  • Pyrantel
Possible Side Effects
Active Ingredient
Directions for use
  • It can be given with or without food intake.
  • It's a small, hard, but chewable tablet.

Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea.

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